Postdoctoral Fellow-MSH
Roles & Responsibilities:
This PostDoc position is available with Dr. Rosalind Wright’s research group at the Icahn School of Medicine at Mount Sinai in New York City (NYC). This is an exciting opportunity to join a mature transdisciplinary team science environment embedded in a vibrant exposomic ecosystem in our Institute for Exposomic Research. Funding is guaranteed for 2 years with potential for further support. Dr. Wright’s research program leverages ongoing pregnancy cohort studies investigating the impact of prenatal and early childhood exposures (both chemical and non-chemical) on child developmental outcomes including growth and obesity, respiratory disorders including asthma and lung development, neurocognition and behavioral development, emerging psychological dysfunction including internalizing/ externalizing problems and sleep disorders in preschool and early school-aged children. Chemical exposures include toxic metals and their mixtures, ambient air pollution and their mixtures, and organic chemicals with an extensive biorepository to facilitate expanded exposure assessment.Consideration of modifying effects of nutrition is a major developing interest among the group. We have substantial infrastructure facilitating geocoding and linkage with administrative databases to consider community factors such as crime/violence, access to healthy foods, green space, etc. A particular focus is on developing a platform to allow multi-omic approaches to interrogating these complex associations and their biologic underpinnings including available data on extracellular vesicle-related microRNAs and long noncoding RNAs, as well as proteomic, mitochondriomic, metablomic, epigenomic dataMetabolomics and microbiome are also of interest. This program is funded through multiple R01 studies and are part of the NIH funded national ECHO (Environmental Influences on Children’s Health Outcomes) program. Other notable support includes a NIEHS-funded K12 program, NCATS funded KL2/Tl1 training programs, and a NIEHS P30 Center Grant all of which provide opportunities for pilot funding available to postdocs throughout training. These programs provide significant support for the postdoctoral candidates to submit a NIH funded Career Development Award or other grant mechanism to facilitate transition to independence. The successful postdoc will lead epidemiology and computational investigations incorporating exposomic approaches leveraging this reach ecosystem.
Examples of active projects include:
1. Prenatal metal-stress mixtures and transdiagnostic pathways to preadolescent internalizing disorders: Role of placental molecular signaling
2. Prenatal metal mixtures and neurodevelopment: Role of placental extracellular microRNAs
3. ECHO consortium on Perinatal Programming of Neurodevelopment
4. Maternal traumatic stress, oxidative stress, antioxidant exposures, and child asthma and lung function
5. Prenatal metals-stress mixtures and sleep disruption in preschoolers
Requirements:
Applicants should possess a Ph.D. in Environmental and/or Molecular Epidemiology, Social Epidemiology, Nutritional Epidemiology, Developmental Psychology, or in other relevant disciplines, such as Statistics/Biostatistics, Computational Biology, Machine Learning, or Bioinformatics, with relevant previous work and interest in environmental health. Strong quantitative skills relevant to this broad program such as practical experience working with complex epidemiology data, familiarity with the R statistical software packages and excellent oral communication and scientific writing are desirable. Experience with high dimensional molecular data such as metabolomics, mitochondriomics, Illumina BeadChip methylation (450K, 850K or EPIC) and RNA-seq data is a strength.
Interested individuals should send a cover letter, curriculum vitae, two sample publications, and the names/phone numbers of three people who could provide letters of reference by email to Ms. Suzy Allen, Administrative Manager: Suzy.Allen@mssm.edu.
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