Principal Data Strategist, Real World Evidence (RWE)

Skip to main contentDashboardProfileJoin Talent NetworkSign InEnglishSingle PositionView All JobsPrincipal Data Strategist, Real World Evidence (RWE)Marlborough US-MA, United States | US-MA-Marlborough, US-MN-Arden Hills No longer accepting applications.Work ModeHybridRequisition ID629425Additional Location(s): US-MA-Marlborough; US-MN-Arden HillsDiversity - Innovation - Caring - Global Collaboration - Winning Spirit - High PerformanceAt Boston Scientific, we’ll give you the opportunity to harness all that’s within you by working in teams of diverse and high-performing employees, tackling some of the most important health industry challenges. With access to the latest tools, information and training, we’ll help you in advancing your skills and career. Here, you’ll be supported in progressing – whatever your ambitions.       About the role:The Principal Data Strategist, Real World Evidence (RWE) will lead enterprise real-world data (RWD) strategy and advanced analytics initiatives that support scalable, regulatory-aligned evidence generation across Boston Scientific. This role combines strategic leadership in data sourcing, vendor assessment, governance, and long-term data planning with deep expertise in real-world evidence, epidemiology, and data science.This incumbent will be operating with a high degree of autonomy, this individual will shape fit-for-purpose RWD strategies, evaluate and operationalize external data assets, and lead advanced analytics initiatives using EHRs, claims, registries, and linked healthcare data. The role partners closely with Clinical, Medical Affairs, Regulatory, HEMA, IT, Biostatistics, Quality, and R&D stakeholders to advance both immediate evidence generation priorities and long-term data capabilities.Work model, sponsorship, relocation:At Boston Scientific, we value collaboration and synergy. This role follows a hybrid work model requiring employees to be in our local office at least three days per week at our Marlborough, MA or Arden Hills, MN office. Boston Scientific will not offer sponsorship or take over sponsorship of an employment visa for this position at this time. Relocation assistance is not available for this position at this time.Your responsibilities will include:Data Strategy & Vendor ManagementSupport enterprise RWD strategy development and long-term data planning aligned with evidence generation priorities.Evaluate and operationalize external data assets including EHR, claims, registry, and emerging healthcare data sources.Lead vendor assessments and data source evaluations including quality, linkage feasibility, scalability, governance, and regulatory suitability.Partner cross-functionally to support data acquisition, governance, integration, and scalable analytics infrastructure.Provide strategic guidance on fit-for-purpose data selection, feasibility assessments, and analytic approaches.Study Design & Execution Lead the design, development, and evaluation of RWE study protocols, including cohort definitions, endpoints, and analytic plans. Collaborate with KOLs and stakeholders to ensure robust analytical approaches and clinically meaningful outputs.Validate methodologies and results, ensuring transparency, reproducibility, and audit-readiness.Apply rigorous epidemiologic and statistical methods to address bias, confounding, and data limitations. Translate study findings into impactful reports and actionable insights to support evidence generation, value messaging, publications, regulatory submissions, and strategic decision-making. Ensure alignment of study design and execution with regulatory and methodological guidance. Oversee feasibility assessments, including data availability, fit-for-purpose evaluations, and study design optimization. Execute end-to-end RWE studies, from protocol development through analysis, interpretation, and dissemination of results. Advanced Analytics, Communication & LeadershipDevelop advanced analytics solutions including predictive modeling,...