Development Head, Respiratory

United StatesFull-time$330k–$550kPosted Aug 5, 2026

Position Summary

The Development Head, Respiratory will be a pivotal leader within Pfizer’s Research & Development Inflammation & Immunology (I&I) Division, reporting to the Chief Development Officer for I&I. This role will set and execute a compelling vision for Respiratory, driving the development of groundbreaking therapies, shaping the overall strategy. The leader will oversee end-to-end clinical program performance, including protocol development and robust trial execution, while building a world-class pipeline from internal and external sources. As part of the I&I leadership team, the Development Head will provide strategic direction, foster cross-functional collaboration, and mentor a high-performing global Development team. The successful candidate will be a hands-on thought leader with deep expertise in respiratory and clinical development, committed to delivering patient-focused, data-driven innovation. This position is based in Cambridge, Massachusetts.

Key responsibilities include:

  • Strategic Oversight & Vision: Shape and drive the strategic direction for I&I clinical programs in Respiratory. As a member of the I&I Development leadership team, is a critical part and driver of the overall I&I strategy and Development leadership.
  • Team Leadership & Culture: Inspire, mentor, and develop the program and clinical leaders in Respiratory, fostering an environment of innovation, accountability, and continuous learning, while championing Pfizer’s commitment to patient-centricity, entrepreneurial thinking, and data-driven excellence.
  • Clinical Programs: Drive the adoption of innovative trial designs to enhance clinical impact and accelerate value creation. Accountable for the planning and performance of all clinical programs in Respiratory from Phase 1 onwards to live cycle management.
  • External Engagement: Act as a visible ambassador for Respiratory at Pfizer at scientific conferences articulating the Company’s vision and cultivating strong relationships with KOLs, CROs, academic collaborators, and regulatory stakeholders.
  • Cross-Functional Partnership: Work cross-functionally with Medical Affairs, Regulatory, Safety, Operations, and Business Development and the Commercial organization to align and integrate clinical strategies and standards across the I&I portfolio.
  • Industry Foresight: Continuously scan and interpret the evolving scientific and competitive landscape, leveraging emerging technologies and disruptive trends to inform and evolve Pfizer’s clinical strategy in I&I.

Requirements:

  • M.D. with at least 10 years’ experience leading development respiratory clinical trials including early and late projects, including submissions.
  • Proven success in I&I clinical project/program leadership.
  • Deep understanding of I&I drug development, protocol writing, study conduct, data analysis, and regulatory submissions.
  • Strong leadership and interpersonal skills, with demonstrated ability to manage and mentor teams and collaborate with diverse stakeholders in I&I.
  • Experience with global I&I regulatory submissions and interactions with major regulatory agencies.
  • Demonstrated experience engaging with CROs, KOLs, regulatory authorities, and the broader I&I research community.
  • Track record of leveraging data, technology, and innovative approaches to scale clinical operations and deliver value for patients.

The annual base salary for this position ranges from $330,200.00 to $550,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.




Relocation assistance may be available based on business needs and/or eligibility.




Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.




Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.




EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.




To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.


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