Production Sequencing Lead

Production Sequencing Lead LocationLondonEmployment TypeFull timeLocation TypeOn-siteDepartmentGlobal ResearchAbout usBasecamp Research is dedicated to solving major challenges in the life sciences by exploring Beyond Known Biology. Our teams build frontier AI models using BaseData, the world's largest ethically-sourced and globally representative biological dataset. Our Global Research Team collects and curates our own biological data through partnerships with more than 152 organizations in 28 countries, giving its AI access to genetic diversity that doesn't exist for models trained on public database sources. This enables Basecamp Research to design novel protein sequences and biological systems that can accelerate therapeutic research and development. In October 2024 we closed Series B and in January 2026 finalised pre-Series C investment from NVIDIA. With hubs both in London, UK as well as Boston Massachusetts, USA and partners with biopharma companies and academic institutions worldwide, our work has been recognized with honors including Fast Company's Top 10 Most Innovative Companies in Biotech and the FT-backed Sifted AI100 list of Europe's leading AI startups. At Basecamp Research, we pride ourselves on being a diverse, exciting, fun, and flexible place to work. Our team of biologists, engineers, ML scientists, field explorers, and operations specialists are united by a sense of adventure and the belief that nature has already designed the solutions to our planet’s greatest challenges - we just need to go out and discover them! If you feel passionate about the power of biology, data, and AI to build a better world, we’d love to hear from you.The RoleThis role is the operational spine of the Trillion Gene Atlas. You will own the sample-to-sequence pipeline end-to-end, driving throughput, translating R&D into production, and leading the team that keeps the Atlas growing.Own the TGA production pipeline. Provide agile, end-to-end management of the sample processing pipeline across Phase 1 and Phase 2 - from DNA extraction through library preparation and sequencing dispatch. You set the pace and hold the targets.Lead technical transfer from R&D into production. Work closely with our R&D team to translate validated protocols into robust, scalable production workflows. You are the bridge between experimental and operational - ensuring new methods land cleanly and run reliably at volume.Drive continuous improvement. Apply Lean / Six Sigma principles to continuously improve turnaround times, reduce variability, and increase throughput. Identify bottlenecks, implement fixes, and build improvements back into the standard workflow.Monitor data input and pipeline health. Work with data suppliers and internal bioinformatics teams to ensure smooth, high-quality data return from sequencing partners. Track key metrics, flag issues early, and close the loop between production and downstream analysis.Lead and develop the production team. You will be the operational lead for the TGA lab team - managing day-to-day workflow, mentoring junior staff, and building a culture of precision, accountability, and pace as we scale through Phase 2.Horizon scan and deploy new technologies. Stay ahead of emergent sequencing technologies, automation platforms, and workflow innovations. Evaluate fit for TGA production targets and move and sync quickly to pilot and implement where there is clear operational value.Required Skills and Experience5+ years working in a production-based environment for high-throughput sequencing, with a confident track record running a small team to deliver high-impact work on time.Deep familiarity with short-read (Illumina / Ultima) and long-read (PacBio / Nanopore) platforms and library preparation workflows end-to-end.Demonstrable track record applying Lean / Six Sigma in a laboratory production setting - waste reduction, throughput improvement, SOP development.Experience with laboratory automation - developing, validating,...