Discovery Process Chemistry Scale-Up Research Scientist

Skip to main contentSign InDiscovery Process Chemistry Scale-Up Research Scientist page is loadedDiscovery Process Chemistry Scale-Up Research ScientistApplylocationsSan Diego, CAtime typeFull timeposted onPosted 30+ Days Agojob requisition idREQ-28845Job DescriptionThe Discovery Process Chemistry Research Scientist will work as part of the Scale-up group in Medicinal Chemistry to synthesize compounds on a range of scales from multigrams to hundreds of grams for biological evaluation. Performs experimental troubleshooting and synthetic route development with the ability to execute complex experimental procedures. Completes work in a resourceful, self-sufficient and timely manner and is able to design alternative approaches to achieve desired outcomes. Keeps up to date with current scientific literature and technologies relevant to their field of technical expertise. This is an onsite position at our San Diego research site.Key Duties and Responsibilities:Design and undertake experimental synthetic work as part of the scale-up group to deliver material for internal customers working on 10s grams to 100s grams scale.Personally deliver material and independently develop and optimize processes.Work within the Scale-up group to enable rapid delivery of material, problem solve and share knowledge.Collates and interprets complex data systematically, and organizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities.Exercises solid judgment to prioritize studies, considering feasibility and Project impact.Performs advanced and/or complex experimental troubleshooting.Scours relevant scientific literature and routinely incorporates new insights into research activities.Identifies, prioritizes and introduces relevant emerging technologies in their field of expertise to advance the existing technology platforms and create/maintain a competitive advantage.Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals.Contributes significantly to patent and/or publication preparation.Independently prepares study presentations and presents experimental conclusions.Knowledge and Skills:Experience of working in a large-scale, synthetic laboratory to deliver complex organic compoundsDisplay a flexible approach and be comfortable working on a variety of scalesExperience using ≥ 5L glasswareStrong interpersonal skills and a team playerSome experience and understanding of process safety and hazard assessment. A diligent approach to all safety matters.Very strong synthetic chemistry knowledge and mechanistic understandingEducation and Experience LevelPhD or post-doc with 0 - 3 years of experience in a relevant area of research, or the equivalent industrial experienceBS and 6+ years of experienceMS and 3 years of experience, or#LI-KM1#LI-OnsitePay Range:$104,000 - $156,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and...